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Aneuploidy Screening

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Preimplantation genetic aneuploidy screening (PGS) has been performed as a way of enhancing embryo selection in patients with an increased incidence of embryonic numerical chromosome abnormalities (advanced maternal age, recurrent miscarriage and recurrent implantation failure). It has been proposed that the replacement of euploid embryos in these patients would result in a higher implantation and pregnancy rate and a reduced miscarriage rate. Additionally, the transfer of fewer embryos could reduce the chances for multiple pregnancies in all IVF patients. Although, to date, multiple studies have addressed this issue, contradictory results have been encountered. As a result, the effectiveness of aneuploidy screening remains to be established. Moreover, child outcome studies documenting the safety of this procedure are needed.

For couples aware of genetic disorders through family history or based on carrier testing, PGD testing can be performed to help avoid a pregnancy or child born with the specified genetic condition. In genetic disorders where the gene structure is known, such as Cystic Fibrosis or Tay-Sachs, the actual genes of the embryo are examined for presence of the condition. Other genetic disorders, such as Duchenne muscular dystrophy or hemophilia, only affect males and, therefore, the DNA of the embryo is examined to determine the sex and only the female embryos are transferred.

PGS can currently be used to detect the following single gene disorders:

Cystic Fibrosis
Sickle Cell Anemia
Thalassemia
Tay Sachs Disease
Myotonic Dystrophy
Fragile X Syndrome
Phenylketonuria (PKU)
Gaucher's Disease
Retinoblastoma
Hemophilia
ADA Deficiency

Multiple Epiphyseal Dysplasia
Fanconi Anemia
Alzheimer’s
Retinitis Pigmentosa
Epidermolysis Bullosa
Duchenne's muscular dystrophy
OTC Deficiency
Achondroplasis
LCHAD
X-Linked Hydrocephalus

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FERTILITY TREATMENT OPTIONS

	FERTILITY TREATMENTS Fertility treatment options that are result driven and affordable.
	GENETIC SCREENING PGD involves carefully removing one or more cells from an embryo for analysis.
	GENDER SELECTION PGD Gender Selection is a procedure that enables couples to choose the sex of their baby.
	CRYOPRESERVATION Egg freezing program for women who are planning to use their own eggs in the future.
	PATIENT GUIDE There are many things you should know about before embarking on a journey.

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